Prognostic Impact of the Combination of Recurrence Score and Quantitative Estrogen Receptor Expression (ESR1) on Predicting Late Distant Recurrence Risk in Estrogen Receptor–Positive Breast Cancer After 5 Years of Tamoxifen: Results From NRG Oncology/National Surgical Adjuvant Breast and Bowel Project B-28 and B-14

PURPOSE: We determined the utility of the 21-Gene Recurrence Score (RS) in predicting late (> 5 years) distant recurrence (LDR) in stage I and II breast cancer within high and low-ESR1–expressing groups. PATIENTS AND METHODS: RS was assessed in chemotherapy/tamoxifen-treated, estrogen receptor (E...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Wolmark, Norman, Mamounas, Eleftherios P., Baehner, Frederick L., Butler, Steven M., Tang, Gong, Jamshidian, Farid, Sing, Amy P., Shak, Steven, Paik, Soonmyung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981975/
https://ncbi.nlm.nih.gov/pubmed/27217450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.62.6630
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