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Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Adenovirus vectors are potent tools for genetic vaccination and oncolytic virotherapy. However, they are prone to multiple undesired vector-host interactions, especially after in vivo delivery. It is a consensus that the limitations imposed by undesired vector-host interactions can only be overcome...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Jönsson, Franziska, Hagedorn, Claudia, Kreppel, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235605/
https://ncbi.nlm.nih.gov/pubmed/30417881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58480
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