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High-throughput Measurement of Gut Transit Time Using Larval Zebrafish

Zebrafish are used as alternative model organisms for drug safety testing. The gastrointestinal (GI) tract of zebrafish has genetic, neuronal, and pharmacological similarities to that of the mammals. GI intolerance during clinical testing of drug candidates is common and may pose a serious threat to...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Cassar, Steven, Huang, Xin, Cole, Todd
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235591/
https://ncbi.nlm.nih.gov/pubmed/30417875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58497
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