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High-throughput Measurement of Gut Transit Time Using Larval Zebrafish

Zebrafish are used as alternative model organisms for drug safety testing. The gastrointestinal (GI) tract of zebrafish has genetic, neuronal, and pharmacological similarities to that of the mammals. GI intolerance during clinical testing of drug candidates is common and may pose a serious threat to...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Cassar, Steven, Huang, Xin, Cole, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235591/
https://ncbi.nlm.nih.gov/pubmed/30417875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58497
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