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Inhibition enhances spatially-specific calcium encoding of synaptic input patterns in a biologically constrained model

Synaptic plasticity, which underlies learning and memory, depends on calcium elevation in neurons, but the precise relationship between calcium and spatiotemporal patterns of synaptic inputs is unclear. Here, we develop a biologically realistic computational model of striatal spiny projection neuron...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Dorman, Daniel B, Jędrzejewska-Szmek, Joanna, Blackwell, Kim T
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235562/
https://ncbi.nlm.nih.gov/pubmed/30355449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38588
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