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Inhibition enhances spatially-specific calcium encoding of synaptic input patterns in a biologically constrained model

Synaptic plasticity, which underlies learning and memory, depends on calcium elevation in neurons, but the precise relationship between calcium and spatiotemporal patterns of synaptic inputs is unclear. Here, we develop a biologically realistic computational model of striatal spiny projection neuron...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Dorman, Daniel B, Jędrzejewska-Szmek, Joanna, Blackwell, Kim T
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235562/
https://ncbi.nlm.nih.gov/pubmed/30355449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38588
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