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A chronic myeloid leukemia case with a variant translocation t(11;22) (q23;q11.2): masked Philadelphia or simple variant translocation?

Chronic myeloid leukemia (CML) is characterized by the presence of the Philadelphia chromosome (Ph), usually due to a reciprocal translocation, t(9;22)(q34;q11.2). The remaining cases (2-10%) have variant translocation, and more rarely (~1%) a cryptic rearrangement is present which can be detected b...

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Detalhes bibliográficos
Publicado no:Pan Afr Med J
Main Authors: Acar, Kadir, Uz, Burak
Formato: Artigo
Idioma:Inglês
Publicado em: The African Field Epidemiology Network 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235488/
https://ncbi.nlm.nih.gov/pubmed/30455790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11604/pamj.2018.30.161.9318
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