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Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome

Myelodysplastic syndromes (MDS) are a diverse group of hematopoietic stem cell disorders that are defined by ineffective hematopoiesis, peripheral blood cytopenias, dysplasia, and a propensity for transformation to acute leukemia. NUP98-HOXD13 (NHD13) transgenic mice recapitulate human MDS in terms...

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Publicado en:J Vis Exp
Autores principales: Chung, Yang Jo, Khawaja, Ghanwa, Wolcott, Karen M., Aplan, Peter D.
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235411/
https://ncbi.nlm.nih.gov/pubmed/30346380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58140
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