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The pharmacokinetics of dexmedetomidine in patients with obstructive jaundice: A clinical trial
OBJECTIVES: Dexmedetomidine, a highly selective central α(2)-agonist, undergoes mainly biotransformation in the liver. The pharmacokinetics of dexmedetomidine were significantly affected by hepatic insufficiency. The clearance of dexmedetomidine in patients with severe hepatic failure decreased by 5...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6235379/ https://ncbi.nlm.nih.gov/pubmed/30427948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207427 |
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