Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation

BACKGROUND: Neutrophil extracellular trap (NET) formation has been described to be closely involved in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we aimed to investigate the effect of polydatin (PD) on NET formation and its effects on disease activity in lupus-prone mouse...

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Dettagli Bibliografici
Pubblicato in:Arthritis Res Ther
Autori principali: Liao, Pan, He, Yi, Yang, Fangyuan, Luo, Guihu, Zhuang, Jian, Zhai, Zeqing, Zhuang, Lili, Lin, Zhuomiao, Zheng, Jiehuang, Sun, Erwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235205/
https://ncbi.nlm.nih.gov/pubmed/30419963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1749-y
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