Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation

BACKGROUND: Neutrophil extracellular trap (NET) formation has been described to be closely involved in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we aimed to investigate the effect of polydatin (PD) on NET formation and its effects on disease activity in lupus-prone mouse...

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Bibliografske podrobnosti
izdano v:Arthritis Res Ther
Main Authors: Liao, Pan, He, Yi, Yang, Fangyuan, Luo, Guihu, Zhuang, Jian, Zhai, Zeqing, Zhuang, Lili, Lin, Zhuomiao, Zheng, Jiehuang, Sun, Erwei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235205/
https://ncbi.nlm.nih.gov/pubmed/30419963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1749-y
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