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Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin

In Drosophila, the piRNAs that guide germline transposon silencing are produced from heterochromatic clusters marked by the HP1 homolog Rhino. We show that Rhino promotes cluster transcript association with UAP56 and the THO complex, forming RNA-protein assemblies that are unique to piRNA precursors...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Zhang, Gen, Tu, Shikui, Yu, Tianxiong, Zhang, Xiao-Ou, Parhad, Swapnil S., Weng, Zhiping, Theurkauf, William E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235161/
https://ncbi.nlm.nih.gov/pubmed/30257203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.081
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