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Re-evaluation of Mouse Tissue Factor Pathway Inhibitor and Comparison of Mouse and Human Tissue Factor Pathway Inhibitor Physiology

BACKGROUND: Mouse models can provide insight into the pathophysiology of human thrombosis and hemostasis. Tissue factor pathway inhibitor (TFPI) regulates coagulation through protein S (PS)-enhanced factor (F)Xa inhibition and FXa-dependent inhibition of FVIIa/tissue factor (TF) activity. TFPI is ex...

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Podrobná bibliografie
Vydáno v:J Thromb Haemost
Hlavní autoři: Girard, Thomas J., Grunz, Kristin, Lasky, Nina M., Malone, James P., Broze, George J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235150/
https://ncbi.nlm.nih.gov/pubmed/30194803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14288
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