PEP-1-paraoxonase 1 fusion protein prevents cytokine-induced cell destruction and impaired insulin secretion in rat insulinoma cells

Pancreatic beta cell destruction and dysfunction induced by cytokines is a major cause of type 1 diabetes. Paraoxonase 1 (PON1), an arylesterase with antioxidant activity, has been shown to play an important role in preventing the development of diabetes in transgenic mice. However, no studies have...

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Vydáno v:BMB Rep
Hlavní autoři: Lee, Su Jin, Kang, Hyung Kyung, Choi, Yeon Joo, Eum, Won Sik, Park, Jinseu, Choi, Soo Young, Kwon, Hyeok Yil
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235087/
https://ncbi.nlm.nih.gov/pubmed/30269741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.10.181
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