PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson’s Disease

Parkinson’s disease (PD) is characterized mainly by the loss of dopaminergic neurons in the substantia nigra (SN) mediated via oxidative stress. Although glutaredoxin-1 (GLRX1) is known as one of the antioxidants involved in cell survival, the effects of GLRX1 on PD are still unclear. In this study,...

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Veröffentlicht in:Molecules
Hauptverfasser: Choi, Yeon Joo, Kim, Dae Won, Shin, Min Jea, Yeo, Hyeon Ji, Yeo, Eun Ji, Lee, Lee Re, Song, Yejin, Kim, Duk-Soo, Han, Kyu Hyung, Park, Jinseu, Lee, Keun Wook, Park, Jong Kook, Eum, Won Sik, Choi, Soo Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198499/
https://ncbi.nlm.nih.gov/pubmed/34206041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113329
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