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Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis

Metal-catalyzed cross-coupling reactions are extensively employed in both academia and industry for the synthesis of biaryl derivatives for applications to both medicine and material science. Application of these methods to prepare tetra-ortho-substituted biaryls leads to chiral atropisomeric produc...

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Bibliografiske detaljer
Udgivet i:ACS Catal
Main Authors: Patel, Nitinchandra Dahyabhai, Sieber, Joshua D., Tcyrulnikov, Sergei, Simmons, Bryan J., Rivalti, Daniel, Duvvuri, Krishnaja, Zhang, Yongda, Gao, Donghong A., Fandrick, Keith R., Haddad, Nizar, Lao, Kendricks So, Mangunuru, Hari Prasad Reddy, Biswas, Soumik, Qu, Bo, Grinberg, Nelu, Pennino, Scott, Lee, Heewon, Song, Jinhua J., Gupton, B. Frank, Garg, Neil K., Kozlowski, Marisa C., Senanayake, Chris H.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234982/
https://ncbi.nlm.nih.gov/pubmed/30450265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b02509
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