Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia

Glial connexins (Cxs) form gap junction channels through which a pan-glial network plays key roles in maintaining homeostasis of the central nervous system (CNS). In multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), expression of astrocytic Cx43 is lost i...

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Pubblicato in:Front Immunol
Autori principali: Fang, Mei, Yamasaki, Ryo, Li, Guangrui, Masaki, Katsuhisa, Yamaguchi, Hiroo, Fujita, Atsushi, Isobe, Noriko, Kira, Jun-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234958/
https://ncbi.nlm.nih.gov/pubmed/30464764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02588
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