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Biaryl scaffold-focused virtual screening for anti-aggregatory and neuroprotective effects in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a primary cause of dementia in ageing population affecting more than 35 million people around the globe. It is a chronic neurodegenerative disease caused by defected folding and aggregation of amyloid beta (Aβ) protein. Aβ is formed by the cleavage of membrane...

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Podrobná bibliografie
Vydáno v:BMC Neurosci
Hlavní autoři: Khalid, Sidra, Zahid, Muhammad Ammar, Ali, Hussain, Kim, Yeong S., Khan, Salman
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234579/
https://ncbi.nlm.nih.gov/pubmed/30424732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0472-6
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