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When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter

Mutational profiling has fundamentally changed our approach to patients with acute myeloid leukemia (AML). Patients with AML are routinely profiled for the presence of mutations in FLT3, NPM1, CEBPA, and, more recently, TP53. In this chapter, we review the role of mutational profiling to help define...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Roloff, Gregory W., Griffiths, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234366/
https://ncbi.nlm.nih.gov/pubmed/30425072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020206
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