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When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter

Mutational profiling has fundamentally changed our approach to patients with acute myeloid leukemia (AML). Patients with AML are routinely profiled for the presence of mutations in FLT3, NPM1, CEBPA, and, more recently, TP53. In this chapter, we review the role of mutational profiling to help define...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Roloff, Gregory W., Griffiths, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234366/
https://ncbi.nlm.nih.gov/pubmed/30425072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020206
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