Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo

Dyslipidemia is a risk factor for clinically significant thrombotic events. In this condition, scavenger receptor CD36 potentiates platelet reactivity through recognition of circulating oxidized lipids. CD36 promotes thrombosis by activating redox-sensitive signaling molecules, such as the MAPK extr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Yang, Moua, Kholmukhamedov, Andaleb, Schulte, Marie L., Cooley, Brian C., Scoggins, Na’il O., Wood, Jeremy P., Cameron, Scott J., Morrell, Craig N., Jobe, Shawn M., Silverstein, Roy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234364/
https://ncbi.nlm.nih.gov/pubmed/30381401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018025411
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados