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Nitric oxide triggers the assembly of “type II” stress granules linked to decreased cell viability

We show that 3-morpholinosydnonimine (SIN-1)-induced nitric oxide (NO) triggers the formation of SGs. Whereas the composition of NO-induced SGs is initially similar to sodium arsenite (SA)-induced type I (cytoprotective) SGs, the progressive loss of eIF3 over time converts them into pro-death (type...

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Pubblicato in:Cell Death Dis
Autori principali: Aulas, Anaïs, Lyons, Shawn M., Fay, Marta M., Anderson, Paul, Ivanov, Pavel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234215/
https://ncbi.nlm.nih.gov/pubmed/30425239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1173-x
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