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The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach
Genome instability is a characteristic of most cancers, contributing to the acquisition of genetic alterations that drive tumor progression. One important source of genome instability is linked to telomere dysfunction in cells with critically short telomeres that lack p53-mediated surveillance of ge...
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| Udgivet i: | J Theor Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6234035/ https://ncbi.nlm.nih.gov/pubmed/30315815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2018.09.003 |
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