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Evolutionary dynamics of feedback escape and the development of stem-cell–driven cancers
Cancers are thought to arise in tissue stem cells, and similar to healthy tissue, are thought to be maintained by a small population of tumor stem or initiating cells, whereas the majority of tumor cells are more differentiated with limited replicative potential. Healthy tissue homeostasis is achiev...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223454/ https://ncbi.nlm.nih.gov/pubmed/22084071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107621108 |
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