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Effect of cell cycle duration on somatic evolutionary dynamics

Cellular checkpoints prevent damage and mutation accumulation in tissue cells. DNA repair is one mechanism that can be triggered by checkpoints and involves temporary cell cycle arrest and thus delayed reproduction. Repair‐deficient cells avoid this delay, which has been argued to lead to a selectiv...

詳細記述

保存先:
書誌詳細
出版年:Evol Appl
主要な著者: Wodarz, Dominik, Goel, Ajay, Komarova, Natalia L.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680637/
https://ncbi.nlm.nih.gov/pubmed/29151865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12518
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