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Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line

BACKGROUND: Triptolide induces apoptosis and DNA damage followed by inhibition of DNA repair associated gene expression. However, there is the limited data for biomarker to predict the benefit to triptolide in various cancers including pancreatic cancer. METHODS: We investigated the anti tumor effic...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kim, Seung Tae, Kim, Sun Young, Lee, Jeeyun, Kim, Kyung, Park, Se Hoon, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Park, Joon Oh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233492/
https://ncbi.nlm.nih.gov/pubmed/30419860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4995-0
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