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Antitumor activity of sorafenib plus CDK4/6 inhibitor in pancreatic patient derived cell with KRAS mutation

KRAS mutation has been known as crucial marker for growth and maintenance of pancreatic cancer (PC) and targeting the KRAS is inevitable component for realizing precision medicine to PC. We established patient-derived tumor cells (PDCs) from patient with KRAS G12R mutant PC. Through the PDC, we inve...

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Bibliografski detalji
Izdano u:J Cancer
Glavni autori: Lee, Taehyang, Kim, Kyung, Lee, Jeeyun, Park, Se Hoon, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Park, Joon Oh, Kim, Seung Tae
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160685/
https://ncbi.nlm.nih.gov/pubmed/30271501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.26068
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