Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies

BACKGROUND: Combination therapy of linezolid (LZD) and rifampicin (RFP) may be more effective than monotherapy for treating gram-positive bacterial infections, but several studies have suggested that RFP decreases LZD exposures, thereby increasing the risk of therapeutic failure and emergence of LZD...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Pharm Health Care Sci
Autori principali: Hashimoto, Satsuki, Honda, Kyoko, Fujita, Kohei, Miyachi, Yuka, Isoda, Kazuya, Misaka, Ko, Suga, Yukio, Kato, Satoshi, Tsuchiya, Hiroyuki, Kato, Yukio, Okajima, Masaki, Taniguchi, Takumi, Shimada, Tsutomu, Sai, Yoshimichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233381/
https://ncbi.nlm.nih.gov/pubmed/30459957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40780-018-0123-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi