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Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies
BACKGROUND: Combination therapy of linezolid (LZD) and rifampicin (RFP) may be more effective than monotherapy for treating gram-positive bacterial infections, but several studies have suggested that RFP decreases LZD exposures, thereby increasing the risk of therapeutic failure and emergence of LZD...
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| Publicado en: | J Pharm Health Care Sci |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6233381/ https://ncbi.nlm.nih.gov/pubmed/30459957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40780-018-0123-1 |
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