TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

BACKGROUND: Deregulated Hippo signaling has been uncovered to be intricately involved in tumorigenesis. Transcriptional factor TEADs serve as key mediators of Hippo signaling and have been increasingly appreciated as putative oncogenes driving cancer initiation and progression. However, its expressi...

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Publicado en:Cancer Cell Int
Autores principales: Zhang, Wei, Li, Jin, Wu, Yaping, Ge, Han, Song, Yue, Wang, Dongmiao, Yuan, Hua, Jiang, Hongbing, Wang, Yanling, Cheng, Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233371/
https://ncbi.nlm.nih.gov/pubmed/30459528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0675-z
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