TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

BACKGROUND: Deregulated Hippo signaling has been uncovered to be intricately involved in tumorigenesis. Transcriptional factor TEADs serve as key mediators of Hippo signaling and have been increasingly appreciated as putative oncogenes driving cancer initiation and progression. However, its expressi...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Zhang, Wei, Li, Jin, Wu, Yaping, Ge, Han, Song, Yue, Wang, Dongmiao, Yuan, Hua, Jiang, Hongbing, Wang, Yanling, Cheng, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233371/
https://ncbi.nlm.nih.gov/pubmed/30459528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0675-z
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