TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

BACKGROUND: Deregulated Hippo signaling has been uncovered to be intricately involved in tumorigenesis. Transcriptional factor TEADs serve as key mediators of Hippo signaling and have been increasingly appreciated as putative oncogenes driving cancer initiation and progression. However, its expressi...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Zhang, Wei, Li, Jin, Wu, Yaping, Ge, Han, Song, Yue, Wang, Dongmiao, Yuan, Hua, Jiang, Hongbing, Wang, Yanling, Cheng, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233371/
https://ncbi.nlm.nih.gov/pubmed/30459528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0675-z
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