Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes a range of diseases, including fatal invasive infections. However, the mechanisms by which the innate immune system recognizes GAS are not well understood. We herein report that the C-type lectin receptor macrophage induci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Imai, Takashi, Matsumura, Takayuki, Mayer-Lambertz, Sabine, Wells, Christine A., Ishikawa, Eri, Butcher, Suzanne K., Barnett, Timothy C., Walker, Mark J., Imamura, Akihiro, Ishida, Hideharu, Ikebe, Tadayoshi, Miyamoto, Tomofumi, Ato, Manabu, Ohga, Shouichi, Lepenies, Bernd, van Sorge, Nina M., Yamasaki, Sho
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233082/
https://ncbi.nlm.nih.gov/pubmed/30352847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809100115
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