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Unraveling the role of B cells in the pathogenesis of an oncogenic avian herpesvirus

Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes immunosuppression, paralysis, and deadly lymphomas in chickens. In infected animals, B cells are efficiently infected and are thought to amplify the virus and transfer it to T cells. MDV subsequently establishes latency i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bertzbach, Luca D., Laparidou, Maria, Härtle, Sonja, Etches, Robert J., Kaspers, Bernd, Schusser, Benjamin, Kaufer, Benedikt B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233081/
https://ncbi.nlm.nih.gov/pubmed/30337483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813964115
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