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In vitro model for lytic replication, latency, and transformation of an oncogenic alphaherpesvirus
Marek’s disease virus (MDV) is an alphaherpesvirus that causes deadly T-cell lymphomas in chickens and serves as a natural small animal model for virus-induced tumor formation. In vivo, MDV lytically replicates in B cells that transfer the virus to T cells in which the virus establishes latency. MDV...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466724/ https://ncbi.nlm.nih.gov/pubmed/26039998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424420112 |
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