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Flaviviruses have imperfect icosahedral symmetry

Flaviviruses assemble initially in an immature, noninfectious state and undergo extensive conformational rearrangements to generate mature virus. Previous cryo-electron microscopy (cryo-EM) structural studies of flaviviruses assumed icosahedral symmetry and showed the concentric organization of the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Therkelsen, Matthew D., Klose, Thomas, Vago, Frank, Jiang, Wen, Rossmann, Michael G., Kuhn, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233072/
https://ncbi.nlm.nih.gov/pubmed/30348794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809304115
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