Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres

Flaviviruses assemble as fusion-incompetent immature particles and subsequently undergo conformational change leading to release of infectious virions. Flavivirus infections also produce combined ‘mosaic' particles. Here, using cryo-electron tomography, we report that mosaic particles of dengue...

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Detalhes bibliográficos
Main Authors: Plevka, Pavel, Battisti, Anthony J, Junjhon, Jiraphan, Winkler, Dennis C, Holdaway, Heather A, Keelapang, Poonsook, Sittisombut, Nopporn, Kuhn, Richard J, Steven, Alasdair C, Rossmann, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128282/
https://ncbi.nlm.nih.gov/pubmed/21566648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.75
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