Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

Increased tissue stiffness is a classic characteristic of solid tumors. One of the major contributing factors is increased density of collagen fibers in the extracellular matrix (ECM). Here, we investigate how cancer cells biomechanically interact with and respond to the stiffness of the ECM. Probin...

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Publicat a:Mol Biol Cell
Autors principals: Wullkopf, Lena, West, Ann-Katrine V., Leijnse, Natascha, Cox, Thomas R., Madsen, Chris D., Oddershede, Lene B., Erler, Janine T.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2018
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233061/
https://ncbi.nlm.nih.gov/pubmed/30091653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-05-0319
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