Aqueous Extract of Mori Folium Exerts Bone Protective Effect Through Regulation of Calcium and Redox Homeostasis via PTH/VDR/CaBP and AGEs/RAGE/Nox4/NF-κB Signaling in Diabetic Rats

Purpose: The present study is aimed to explore whether the aqueous extract of Mori Folium (MF) exhibits bone protective effect by regulating calcium and redox homeostasis in diabetic rats, and to identify the signaling pathways involved in this process. Methods: Diabetic rats were established using...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Chenyue, Zhu, Ruyuan, Liu, Haixia, Li, Lin, Chen, Beibei, Jia, Qiangqiang, Wang, Lili, Ma, Rufeng, Tian, Simin, Wang, Min, Fu, Min, Niu, Jianzhao, Orekhov, Alexander N., Gao, Sihua, Zhang, Dongwei, Zhao, Baosheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233025/
https://ncbi.nlm.nih.gov/pubmed/30459613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01239
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