Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway

Purpose: This study is designed to explore whether Fructus ligustri lucidi (FLL) exhibits antioxidant effect in ovariectomized (OVX) rats, and to identify the signaling pathway involved in this process. Methods: OVX rats were treated with FLL aqueous extract (3.5 g/kg) for 12 weeks. Serum, uteri, an...

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Udgivet i:Front Pharmacol
Main Authors: Wang, Lili, Ma, Rufeng, Guo, Yubo, Sun, Jing, Liu, Haixia, Zhu, Ruyuan, Liu, Chenyue, Li, Jun, Li, Lin, Chen, Beibei, Sun, Liping, Tang, Jinfa, Zhao, Dandan, Mo, Fangfang, Niu, Jianzhao, Jiang, Guangjian, Fu, Min, Brömme, Dieter, Zhang, Dongwei, Gao, Sihua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438993/
https://ncbi.nlm.nih.gov/pubmed/28588482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00266
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