Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability

Psoralen is a major component of the common traditional Chinese medicine Fructus Psoraleae (FP). In this study, we focused on psoralen to explore FP-induced hepatotoxicity and the underlying mechanisms. The acute oral median lethal dose of psoralen in ICR mice was determined to be 1,673 mg/kg. C57BL...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Zhou, Wang, Chen, Xi, Zhao, Guolin, Xu, Dengqiu, Jiang, Zhenzhou, Zhang, Luyong, Wang, Tao
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232894/
https://ncbi.nlm.nih.gov/pubmed/30459602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01179
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