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Effect of Adoptive Transfer or Depletion of Regulatory T Cells on Triptolide-induced Liver Injury

Objective: The aim of this study is to clarify the role of regulatory T cell (Treg) in triptolide (TP)-induced hepatotoxicity. Methods: Female C57BL/6 mice received either adoptive transfer of Tregs or depletion of Tregs, then underwent TP administration and were sacrificed 24 h after TP administrat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Wang, Xinzhi, Sun, Lixin, Zhang, Luyong, Jiang, Zhenzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840269/
https://ncbi.nlm.nih.gov/pubmed/27148057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00099
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