The Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies

Besides d-serine, another d-amino acid with endogenous occurrence in the mammalian brain, d-aspartate, has been recently shown to influence NMDA receptor (NMDAR)-mediated transmission. d-aspartate is present in the brain at extracellular level in nanomolar concentrations, binds to the agonist site o...

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Vydáno v:Front Psychiatry
Hlavní autoři: Errico, Francesco, Nuzzo, Tommaso, Carella, Massimo, Bertolino, Alessandro, Usiello, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Psychiatry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232865/
https://ncbi.nlm.nih.gov/pubmed/30459655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00559
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