Rheumatoid Arthritis-Associated Autoimmunity Due to Aggregatibacter actinomycetemcomitans and Its Resolution With Antibiotic Therapy

Background: Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutrophils, Aa has been recently linked to rheumatoid a...

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Udgivet i:Front Immunol
Main Authors: Mukherjee, Amarshi, Jantsch, Vanessa, Khan, Rida, Hartung, Wolfgang, Fischer, René, Jantsch, Jonathan, Ehrenstein, Boris, Konig, Maximilian F., Andrade, Felipe
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232707/
https://ncbi.nlm.nih.gov/pubmed/30459755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02352
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