Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

A bacterial etiology of rheumatoid arthritis (RA) has been suspected since the beginnings of modern germ theory. Recent studies implicate mucosal surfaces as sites of disease initiation. The common occurrence of periodontal dysbiosis in RA suggests that oral pathogens may trigger the production of d...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Konig, Maximilian F., Abusleme, Loreto, Reinholdt, Jesper, Palmer, Robert J., Teles, Ricardo P., Sampson, Kevon, Rosen, Antony, Nigrovic, Peter A., Sokolove, Jeremy, Giles, Jon T., Moutsopoulos, Niki M., Andrade, Felipe
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384717/
https://ncbi.nlm.nih.gov/pubmed/27974664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaj1921
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