Anakinra Therapy for Non-cancer Inflammatory Diseases

Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory mediators, including prostaglandins, cytokines, and chemokines. IL-1α is constitutively present in endothelial a...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Cavalli, Giulio, Dinarello, Charles A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232613/
https://ncbi.nlm.nih.gov/pubmed/30459597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01157
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