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Anakinra Therapy for Non-cancer Inflammatory Diseases
Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory mediators, including prostaglandins, cytokines, and chemokines. IL-1α is constitutively present in endothelial a...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6232613/ https://ncbi.nlm.nih.gov/pubmed/30459597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01157 |
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