Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5′ termini

The 5′-cap structure, characteristic for RNA polymerase II-transcribed RNAs, plays important roles in RNA metabolism. In humans, RNA cap formation includes post-transcriptional modification of the first transcribed nucleotide by RNA cap1 methyltransferase (CMTr1). Here, we report that CMTr1 activity...

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Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Toczydlowska-Socha, Diana, Zielinska, Magdalena M., Kurkowska, Malgorzata, Astha, Almeida, Catarina F., Stefaniak, Filip, Purta, Elzbieta, Bujnicki, Janusz M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2018
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232587/
https://ncbi.nlm.nih.gov/pubmed/30397098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0161
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