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Toll-Like Receptor 7 (TLR-7) and TLR-9 Agonists Improve Hepatitis C Virus Replication and Infectivity Inhibition by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are innate immune cells with high antiviral activity triggered by Toll-like receptor 7 (TLR-7) and TLR-9 stimulation. Moreover, they are important mediators between innate and adaptive immunity. Although nowadays there is available an effective therapeutic arsenal...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Dominguez-Molina, B., Machmach, K., Perales, C., Tarancon-Diez, L., Gallego, I., Sheldon, J. L., Leal, M., Domingo, E., Ruiz-Mateos, E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232477/
https://ncbi.nlm.nih.gov/pubmed/30232187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01219-18
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