Recombinant Infectious Bronchitis Viruses Expressing Chimeric Spike Glycoproteins Induce Partial Protective Immunity against Homologous Challenge despite Limited Replication In Vivo

Vaccination regimes against Infectious bronchitis virus (IBV), which are based on a single virus serotype, often induce insufficient levels of cross-protection against serotypes and two or more antigenically diverse vaccines are used in attempt to provide broader protection. Amino acid differences i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Ellis, Samantha, Keep, Sarah, Britton, Paul, de Wit, Sjaak, Bickerton, Erica, Vervelde, Lonneke
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232476/
https://ncbi.nlm.nih.gov/pubmed/30209177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01473-18
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