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Recombinant Infectious Bronchitis Viruses Expressing Chimeric Spike Glycoproteins Induce Partial Protective Immunity against Homologous Challenge despite Limited Replication In Vivo

Vaccination regimes against Infectious bronchitis virus (IBV), which are based on a single virus serotype, often induce insufficient levels of cross-protection against serotypes and two or more antigenically diverse vaccines are used in attempt to provide broader protection. Amino acid differences i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ellis, Samantha, Keep, Sarah, Britton, Paul, de Wit, Sjaak, Bickerton, Erica, Vervelde, Lonneke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232476/
https://ncbi.nlm.nih.gov/pubmed/30209177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01473-18
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